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Isidore » Contact. Isidore is a knowledgable Android (almost 6 years of experience) and mobile developer (Native and hybrid) from Costa Rica (Central America) and has developed for a couple of years before Android.Overweight and obesity in postmenopausal women are associated with type 2 diabetes mellitus, hypertension, dyslipidemia and cardiovascular disease. The underlying cause of these problems is believed to be an imbalance of hormones, including insulin, leptin, estrogen and testosterone.
The mammalian body has two distinct endocrine organs. The hypothalamus is the primary source of neuroendocrine hormones, such as gonadotropin releasing hormone (GnRH) which stimulates the pituitary gland to release luteinizing hormone and follicle-stimulating hormone which, in turn, stimulate ovarian steroidogenesis. The second type of endocrine organ is the pituitary gland, which releases three distinct endocrine hormones, pituitary-releasing hormone, prolactin and adrenocorticotropic hormone, to control the endocrine, metabolic and neurological functions.
The neuroendocrine system controls virtually every aspect of the body’s physiological and biochemical functions. In addition, the neuroendocrine system plays an essential role in many physiological and psychological processes. The neuroendocrine system is responsible for controlling several normal endocrine functions, including ovulation, lactation, and sexual maturation, as well as for controlling metabolic functions, cardiovascular functions and immune system functions. The neuroendocrine system is also responsible for a wide range of abnormalities such as multiple hormone production or secretion, hormone production and secretion outside the normal physiological ranges, obesity and increased appetite.
During the past century a number of endocrine abnormalities have been defined. Growth hormone deficiency, especially in childhood, is now well recognized. Slight abnormalities in thyroid function tests are more often found than frank thyroid failure. Glucocorticoids, both naturally occurring and administered in therapy, lead to Cushing’s syndrome in which the adrenocortical cortex takes up glucose at the expense of cholesterol and triglycerides. Diabetes mellitus is also a biochemical disorder, and an epidemic of noninsulin-dependent diabetes in childhood has been reported.
Despite considerable progress in our understanding of the neuroendocrine system, many questions remain unresolved. These include: the identity of the neuronal cell bodies which control the neurotransmitter secretions, what is the role of serotonin, and why is the pituitary gland so insensitive to the effects of
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